Areas of ResearchArthritis A study in the Journal of the American College of Nutrition examined krill oil (300 mg. daily) compared to a placebo and found that krill oil was effective at reducing arthritis symptoms and inflammation. Tri-KRILL™ offers 500 mg. daily in the two soft gels. Cardiovascular Human clinical studies have demonstrated astaxanthin’s cardiovascular benefit to include a significant decrease in blood serum triglyceride and increase in HDL-cholesterol levels with corresponding increase in serum adiponectin (independent of age) and BMI. Significant increase in ankle brachial pressure index and a significant reduction in both systolic and diastolic blood pressure in healthy postmenopausal women. Significantly increased peripheral capillary blood flow via human blood rheology. Reduced lipid peroxidation in healthy non-smoking men, aged 19-33. In addition, pre clinical animal studies support the human findings as well as establish mechanisms of action. Clinical Trials The clinical benefits of omega-3 fatty acids have been demonstrated in thousands of clinical trials conducted over the past 10 years. In 2008 alone, there were 1000 published papers and over 140 randomized clinical trials on omega-3 fatty acids. During this same period, there were some 15,000 media stories on omega-3 fatty acids. This makes omega-3 fatty acids among the most critically documented nutrients of all those currently under investigation. Several groups have chosen to position krill oil as “better than fish oil.” Our adherence to sound scientific principles has caused us to take a different course. We recognize the tremendous rigor of the science of omega-3 fatty acids. Most of this work has been built on fish oil, while additional work has been built on algae oil, flax oil, krill oil, and other oils. We take the position that fish oil has tremendous benefits-this has been clearly demonstrated over many years of research by many highly qualified investigators. Physical Endurance and Muscle Recovery Research has demonstrated the relationship between astaxanthin supplementation and improved muscle endurance and recovery. In support of this research several studies have suggested possible causal relationships. Two studies, one human and the other animal showed significantly lower serum lactate levels after exercise with use of astaxanthin. In another animal study astaxanthin was found to attenuate exercise-induced damage in skeletal and heart muscle, including inhibition of neutrophil infiltration into the tissues. This study also showed inhibition of reatine kinase activity by the astaxanthin group. Also, in a human rheuology study, astaxanthin supplementation showed significant increase in peripheral blood flow.* Eye Fatigue This area has been well studied with eight human clinicals demonstrating reduced eye fatigue with AstaREAL® astaxanthin showing significant improvement in accommodation, visual acuity and critical flicker fusion. Furthermore, two studies where uveitis was induced demonstrated significant reduction in ciliary body inflammation in subjects administered astaxanthin. Uveitis specifically refers to inflammation of the middle layer of the eye, termed the “uvea” but in common usage may refer to any inflammatory process involving the interior of the eye.* Skin Health Human studies performed in both Japan and the US involving supplementation with AstaREAL® astaxanthin demonstrated significant improvement in skin elasticity, increased moisture content and a reduction in the appearance of fine lines and wrinkles. Immune Response In a study involving an astaxanthin-rich algal meal and vitamin C supplementation with animal subjects, lipid peroxidation significantly decreased and additionally an inhibitory effect was seen on H. pylori growth in vitro. The observed shift from a Th1-response to a mixed Th1/Th2-response is a suggested part of the explanation for the mechanism behind astaxanthin’s effect on H. pylori infected subjects.* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Disclaimer: Information found is presented in good faith with no guarantee or obligation as to accuracy and no assumption of liability. AstaREAL® astaxanthin Powerful Anti-Inflammatory – Several in-vitro and in-vivo studies shows that ASX strongly suppressed nuclear translocation of NFkB inflammatory cascade, which are the leading cause of most degenerative diseases. Provides Superior Mitochondria Protection as research shows that is 1,000 times more effectively than Vitamin E against lipid peroxidation in the mitochondria synergies and protect our endogenous antioxidants from early degradation. Reduce DNA Damage and premature cell death caused by oxidation and plasma C-reactive oxygen. Cross Brain-Retinal Blood Barrier leading to neuro-protective effects and alleviation of eye fatigue. Purest Antioxidant Molecule because it has no-proxidant activity even when subjected to enormous amount of stress from environmental factors and free radicals. |